2025 ICD-10-CM code T88.6
Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered
Medical necessity for the treatment of anaphylaxis is established by the presence of signs and symptoms of a severe allergic reaction, such as airway compromise, hypotension, or urticaria, after the administration of a medication.
The clinician is responsible for recognizing and managing the anaphylactic reaction, which may include administering epinephrine, maintaining airway patency, and providing supportive care.
- Injury, poisoning and certain other consequences of external causes (S00-T88)
- Injury, poisoning and certain other consequences of external causes (T07-T88)Complications of surgical and medical care, not elsewhere classified (T80-T88)
In simple words: This code represents a severe allergic reaction (anaphylaxis) that occurs after a correctly administered medication.
Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered. Use additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5).
Example 1: A patient receives an intravenous antibiotic and develops hives, shortness of breath, and hypotension shortly after administration. The patient is diagnosed with an anaphylactic reaction to the antibiotic., A patient undergoing surgery receives a neuromuscular blocking agent and experiences a sudden drop in blood pressure and bronchospasm. This is identified as an anaphylactic reaction to the medication., A patient receives a dose of pain medication and develops swelling of the face, tongue, and throat, along with difficulty breathing.This severe allergic reaction is consistent with anaphylaxis.
Documentation should include details of the medication administered, the time of administration, the onset and nature of symptoms, and the treatment provided for the anaphylactic reaction. Diagnostic testing, if performed, such as serum tryptase levels, should also be documented.
** Excludes1: anaphylactic reaction due to serum (T80.5-) and anaphylactic shock or reaction due to adverse food reaction (T78.0-). Excludes2: complication following infusion, transfusion and therapeutic injection (T80.-), complication following procedure NEC (T81.-), complications of anesthesia in labor and delivery (O74.-), complications of anesthesia in pregnancy (O29.-), complications of anesthesia in puerperium (O89.-), complications of devices, implants and grafts (T82-T85), complications of obstetric surgery and procedure (O75.4), dermatitis due to drugs and medicaments (L23.3, L24.4, L25.1, L27.0-L27.1), and poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4).
- Specialties:Allergy and Immunology, Emergency Medicine, Anesthesiology, Surgery
- Place of Service:Inpatient Hospital, Outpatient Hospital, Office, Emergency Room - Hospital, Ambulatory Surgical Center