2025 ICD-10-CM code Z79.634
Long-term (current) use of topoisomerase inhibitor.
Medical necessity must be established by demonstrating that the long-term use of topoisomerase inhibitors is a clinically appropriate treatment strategy for the patient's specific condition. The rationale for continued use of these agents should be documented, along with any associated risks and benefits.
In simple words: This code indicates that the patient is currently taking a topoisomerase inhibitor medication, which is often used in chemotherapy, as part of their long-term treatment.
Long-term (current) use of topoisomerase inhibitor drugs such as etoposide, irinotecan, or topotecan.
Example 1: A patient with lung cancer receiving long-term irinotecan treatment., A patient with ovarian cancer on a maintenance dose of topotecan., A patient with leukemia undergoing chronic etoposide therapy.
Documentation should support the long-term use of a topoisomerase inhibitor medication and the underlying condition for which it is being prescribed. This should include details of the diagnosis, treatment plan, and ongoing monitoring of the patient's response to the medication.
** Z79.634 should not be used for short-term or episodic treatment with topoisomerase inhibitors.It signifies ongoing, chronic administration. This code specifically addresses long-term drug use for prophylactic purposes (e.g., cancer recurrence prevention).
- Specialties:Oncology, Hematology
- Place of Service:Office, Inpatient Hospital, Outpatient Hospital, and other places where chemotherapy services are administered.