2025 ICD-10-CM code Z92.21

Personal history of antineoplastic chemotherapy.

A corresponding procedure code should accompany a Z code if a procedure is performed. Z codes are used when circumstances other than a disease, injury, or external cause are recorded as diagnoses or problems.

No modifiers are applicable to Z codes.

The code Z92.21 itself doesn't justify medical necessity for any specific procedure. It serves as a historical marker, and the necessity of any current treatment is determined by the patient's present condition.

This code is used by healthcare providers to document a patient's history of chemotherapy, which can be relevant for various medical decisions, such as assessing risks, monitoring long-term effects, and tailoring future treatment plans.

In simple words: This code indicates the patient has a history of receiving chemotherapy for cancer treatment.

Personal history of antineoplastic chemotherapy. This code indicates that the patient has undergone chemotherapy treatment for cancer in the past.

Example 1: A patient with a history of breast cancer treated with chemotherapy presents for a routine check-up. The code Z92.21 is used to document her past treatment., A patient with a history of leukemia in remission presents with a new infection. Z92.21 is used to note their history of chemotherapy, which might have compromised their immune system., A patient with no active cancer presents with long-term side effects from previous chemotherapy treatment. Z92.21 is used to record the history that explains these side effects.

Documentation should clearly specify the type of cancer for which chemotherapy was administered, the dates of treatment, and any related complications or long-term effects.

** Z92.21 is exempt from the Present on Admission (POA) reporting requirement.

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