2025 ICD-10-CM code D84.81
Immunodeficiency due to conditions classified elsewhere. Code first the underlying condition, such as chromosomal abnormalities, diabetes mellitus, or malignant neoplasms.
Medical necessity for D84.81 is established by the presence of an underlying condition that directly causes the immunodeficiency. Documentation should support the causal link.
The provider is responsible for documenting the underlying condition causing the immunodeficiency and coding it first, followed by D84.81.
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
- Certain disorders involving the immune mechanism (D80-D89)
In simple words: This code is used when a person's immune system is weakened due to another health problem, like a genetic disorder, certain cancers, or diabetes.The code for the underlying health problem should be listed first.
Immunodeficiency due to conditions classified elsewhere. Code first underlying condition, such as: chromosomal abnormalities (Q90-Q99), diabetes mellitus (E08-E13), malignant neoplasms (C00-C96).
Example 1: A patient with Down syndrome (Q90.0) is experiencing recurrent infections due to immunodeficiency. The provider would code Q90.0 first, followed by D84.81., A patient with poorly controlled type 1 diabetes (E10.10) presents with reduced immune function resulting in frequent infections. E10.10 would be coded first, then D84.81., A patient undergoing chemotherapy for leukemia (C95.00) has a weakened immune system. The provider would code C95.00 first, followed by D84.81 to represent the resulting immunodeficiency.
Documentation should clearly establish the underlying condition causing the immunodeficiency. Specific details about the condition and its impact on the immune system should be included.
** This code is not used for immunodeficiency caused by drugs or external factors, which are coded using D84.82.
- Payment Status: Active
- Specialties:Immunology, Internal Medicine, Family Medicine, Oncology, Genetics
- Place of Service:Inpatient Hospital, On Campus-Outpatient Hospital, Off Campus-Outpatient Hospital, Office, Independent Clinic, Federally Qualified Health Center